Friday, July 25, 2014

Exemestane makes you slimmer and more muscular

Exemestane, the active ingredient in Pfizer’s Aromasin,  truly is a body recompositioning drug. At least it is if you’re prepared to accept the results of an Italian study in which 33 women used exemestane for a period of 2 years.

Exemestane is an aromatase inhibitor with a steroid skeleton. Apart from the ethyl group on C6, the compound bears a striking resemblance to Boldenone. If the enzyme aromatase – which converts androstenedione and testosterone into estradiol – tries to provide exemestane with an aromatic ring, it gets so stuck that it breaks down. This is how exemestane lowers oestrogen levels.

Once women with an estradiol-sensitive form of cancer have undergone chemotherapy, an operation and radiation therapy, they usually take anti-oestrogens for five years after that. Most take nolvadex for a couple of years and then go over to an anti-oestrogen like anastrazole or exemestane. Little is known about the long-term effects of exemestane, hence the Italian research.

The researchers monitored 68 older women for 2 years. All the women had already been taking 20 mg nolvadex daily for 2-3 years. Half of them continued with this and the other half started taking 25 mg exemestane per day instead.

The exemestane group built up lean body mass. In the two years that the trial lasted the women in that group gained an average of 2.2 kg lean body mass. And the same group lost an average of 0.7 kg fat.

The triglyceride levels in the blood of the women in the exemestane group went down – a positive development. At the same time exemestane increased the levels of LDL [bad cholesterol] and reduced the concentration of HDL [good cholesterol] – a negative development.

American cancer researchers have offered an explanation of how exemestane might cause these effects. Exemestane itself has almost no androgenic effect, but the researchers announced in 2007 that an exemestane metabolite – the 17beta-hydroxy analogue – is capable of interacting with the androgen receptor.

This means that women should consider carefully whether to use exemestane or not. It also means that exemestane is now of interest to chemical athletes with modest aims.

If men take 25 mg exemestane daily their testosterone level rises by a third, researchers at Farmitalia discovered in the 1980s.

So what would happen if you got men to take 25 mg or 50 mg exemestane daily for a year? And if those men were to do weight training as well?

Friday, July 18, 2014

Women and Trenbolone Use

Trenbolone is one of the most por drugs used by bodybuilders today and, when you look at the stats, it is not hard to see why. A very potent androgen with strong anabolic activity, Trenbolone is an extremely effective hardening and cutting agent. In fact, it is considered indispensable when it comes to pre contest preparation. However, it is also extremely valuable in the off-season as it creates a rapid build up of strength and muscle mass. In fact, the anabolic effect is often compared to testosterone or Dianabol with one very important difference - it does not convert to estrogen. This is what truly sets it apart, as most mass building drugs readily aromatize, leading to many estrogen related problems (e.g. water retention gynecomastia).

Due to the lack of water retention, the gains when using this drug are more easily maintained on discontinuing its use. In addition to this, a very hard and defined appearance can be achieved. Also, since gynecomastia is not an issue, there should not be any need to add an anti-estrogen as long as Trenbolone is the only steroid being used. Due to the highly androgenic nature of this drug an increase in the burning of body fat is observed and a much tighter physique can be achieved without having to resort to extreme dieting.

Trenbolone is more potent than testosterone with an effect being gauged as three times as strong on a milligram for milligram basis. It is also four times as anabolic as Deca-Durabolin - nandrolone decanoate - Durabolin and ten times as androgenic. This makes the majority of the weight gained on this drug lean, quality muscle. Trenbolone also creates an increase in the levels of the hormone IGF-1 (Insulin like Growth Factor-1) which is highly anabolic within muscle tissue. Trenbolone has a stronger binding affinity to the androgen receptor than testosterone. This feature is a major contributing factor to the process of anabolism and fat loss. By promoting nitrogen retention and protein synthesis within the muscle Trenbolone allows the food you eat and the nutritional supplements you take to be used more effectively. It also reduces levels of the catabolic hormone cortisol. Trenbolone is also involved in the production of red blood cells and increases the rate of glycogen replenishment (both of which contribute not only to stamina but also to recovery from workouts)

A reduction in aerobic capacity is the most common complaint with Trenbolone. This is thought to be caused by bronchial dilation resulting from an increase in prostaglandin production. The condition known as "trenbolone Cough" is often a complaint registered with users of the Acetate version (Trenbolone is available in Acetate and Enanthate forms). Androgenic side effects may also be experienced which include oily skin, aggressive behavior, and acne and hair loss. For this reason women are usually advised to stay away from this drug.

It seems that although women are generally told to avoid using this drug, Trenbolone is being used more and more by women in controlled doses. The fact that it adds primarily lean mass whilst reducing body fat is obviously a key factor in its attractiveness. When women were asked for their feedback on Trenbolone use a variety of favored dosages came up. Anything from a very conservative 10mg every other day to a more adventurous 100mg/week split into two doses.

Stacking Trenbolone with Testosterone Propionate was also something favored by those engaging in high level competition. Another use of Trenbolone involved taking it 3-4 days before a show in order to add hardness and definition to the physique. It has to be said that side effects were experienced by all - usually increased hair growth and acne - and the severity of the side effects seemed to be worse in younger women. The theory expressed here being that ovarian function may be the reason for this, with a younger woman still having stronger ovarian function than an older women who may be entering peri-menopause. This is all speculation of course but seems like a plausible explanation in my opinion. Either way, if you are considering using Trenbolone it is advised to use it on its own and at extremely low doses (such as the aforementioned 10mg every other day) in order to test your own unique sensitivity.

Trenbolone is a potent androgen that is primarily used in cattle, so there is even less information at our disposal on this compound or its effects on the female endocrine system than any other drug. It is the one drug that seems to produce results as significant as the side effects that are associated with it. Women are generally advised to stay clear of Trenbolone considering the strong androgenic component which eradicates any possibility of running Trenbolone without sides. The more seasoned female athlete will run it in the off season in order to reap the muscle building benefits of the drug whilst maintaining a relatively low body fat. On the other hand running it during contest preparation will preserve the newly added muscle mass while on a calorie restricted diet. The less daring athlete will run Trenbolone during the last few weeks of contest preparation or even limit their use to the week before the show - with a more frequent injection schedule.

Women who have experienced less favorable side effects on Trenbolone report experiencing tachycardia from a single pin, accompanied by profuse night sweats and insomnia bad enough to bail on the cycle. Others experience rapid hair growth with more frequent shaving (side effects that are far from unmanageable).

Quite honestly, Trenbolone dosing is dependent on how much a woman is willing to deal with in terms of sides. There is no conservative dose for a first timer with Trenbolone being far better suited for the educated, experienced and seasoned athlete who has paid her dues.

It is also important to note that Trenbolone lowers TSH levels so running T3 in conjunction with it is highly advisable, as well as an anti-prolactin such as Dostinex at 0.5mg every third day or 5mg of Bromocriptine daily to keep prolactin levels in check.

Friday, July 11, 2014

GP Stan 50 (Winstrol tabs) by Geneza Pharmaceuticals

GP Stan 50 by Geneza Pharmaceuticals is an oral steroid which contains 50mgs of the hormone stanozolol.

This is the same substance that is suspended in water in GP Stan 50 inj.. The oral preparation of this substance allows bodybuilders to avoid the discomfort of everyday injections which are the normally the protocol with the injectable version. Due to the fact that taking this product with food can cause absorbtion problems, it is recommended that one take GP Stan 50 on an empty stomach for best results. Some bodybuilders also choose to split up their dosage of GP Stan 50 throughout the day in an effort to keep blood levels as consistent as possible.

Winstrol , as it is most popular referred to, is one of the most popular steroids in use today. This drug has very low androgenic properties and very high anabolic properties. GP Stan 50 does not have the ability to aromatize and therefore will not cause any water bloat. This has made this steroid very popular with bodybuilders in the cutting phase of their training.

Users of winstrol often report good gains in strength, vascularity, and muscle tone. People often report very intense muscle "pumps" during workouts when using this compound. This can be attributed to the dynamic protein synthesis and nitrogen retention brought about by the use of this steroid. Some studies have also shown that winstrol has estrogen and progesterone blocking abilities, making it a good choice to use with other steroids such as Testosterone , Deca or Trenbolone.

Winstrol also does a very good job of reducing the amount of SHBG in the body, thus allowing other steroids to be much more abundant in their free state in the body. Due to this fact, GP Stan 10 makes a great addition to all cycles. Winstrol is a C17-alpha alkylated compound, and therefore can be toxic to the liver over time. Because of this, it is recommended that bodybuilders using this compound try to keep dosage in a reasonable range and limit cycle duration to 10wks. There are also several liver protectants and detoxifiers available which should be considered when doing a cycle of this steroid.

Due to its low androgenic activity, GP Stan 50 is a very good choice for women bodybuilders. Males typically use GP Stan 50 in dosages of 40-100mgs a day for a period of 6-8 weeks. 5-10mg a day for a period of 4-6 weeks is the normal dosage range for women.

Friday, July 4, 2014

Recommended Recovery Time Between Anabolic Steroid Cycles

The first factor is that recovery of the HPTA (hypothalamus, pituitary, and testicular axis) from one cycle should always occur fully before starting the next.

Where an anabolic steroid cycle is very short, such as only 2 weeks, steroid cycle recovery can be almost immediate. Well-planned, moderate length steroid cycles, such as only 8 weeks, often allow recovery in a time frame such as only 2 weeks. Long steroid cycles, such as 12 weeks or longer and especially 14 weeks or longer, or poorly planned cycles often have very protracted recoveries.

So first, regardless of what is written below with regard to timing, you should wait until natural testosterone production, without aid of any drug, is back to midnormal levels or better.

Other than this, the time between steroid cycles should be related to duration of anabolic steroid use, including time of clearance after the last injection. Another way of looking at that is the balance between the number of weeks that anabolic steroids are used versus the number of weeks that no steroid is being used.

There really are no black/white cutoff values that anyone can give. Time off versus time on is a gradually sliding scale.

Broadly speaking, I put it this way though: Being “off” twice as many weeks as being “on” is entirely conservative for most who are seeking to build muscle, and absolutely can give great results. Really the only reason to be more conservative than this is if wishing only to maintain. Being “off” about as many weeks as being “on” is moderately aggressive. When the cycles are well-planned, there’s generally no problem with this and, of course, this can give somewhat faster results than the above. And being “off” only half as many weeks as being “on” is about as aggressive as I recommend for the health conscious person. Proper recovery should of course be verified, and blood tests become more important at this frequency of use.

So there’s no one answer, but the above general description has over time proven helpful for many to decide where they wanted to be.

Friday, June 27, 2014

Anabolic Steroids, High Blood Pressure, and the Kidneys

When discussing anabolic steroid use and its known side effects, it is not uncommon to see bodybuilders express concern over potential liver injury or other cardiovascular health issues. However, we are now starting to see a much larger contingent of our community suffering from an equally serious, although less frequently recognized side effect in kidney disease/failure. This is a fairly recent phenomenon, which started in earnest about 10-15 years ago. Although there were certainly documented cases of kidney disease/failure prior to this, they were not nearly as prevalent as they are today. Although there are many potential causes of kidney failure, in this article we are going to limit ourselves to those most often attributed to the bodybuilding lifestyle.

Unfortunately, there is no single cause associated with kidney failure in bodybuilders. Often, it is an accumulative effect brought on by the presence of multiple stressors affecting the body at one time, but before we can pinpoint these causes, we must first understand how steroids affect the body, as well as possess a basic understanding of how the kidneys work to protect the body from toxins.

The kidneys are two bean-shaped organs which sit below the ribcage; one on each side of the spine. Their primary job is to filter the blood of toxins, which they do at a rate of roughly 120-150 quarts of blood per day. From this, they produce about 1-2 quarts of urine, which is then transported from the kidneys to the bladder for disposal.

The kidneys do not work as single, large filtering mechanism. Rather, each one contains about 1 million tiny filtering units called nephrons, which work to purify the blood at a microscopic level. Each of these nephrons contains a tubule, as well as its own filter (called a glomerulus). Just as the digestive system works in a multi-step process to break down food for absorption, nephrons also work through 2–step process to filter the blood. As blood moves through the glomerulus, it allows fluid and waste products to pass through it, while preventing large molecules, such as blood cells and proteins, from doing so. Afterward, this pre-filtered fluid is then sent through the tubules, which further refines the blood by separating toxins from beneficial substances, such as minerals. Ultimately, everything useful is sent back into circulation, while the final concentrated waste product becomes urine.

Let’s pause there for a second and transfer our attention over to a common side effect associated with anabolic steroids use—high blood pressure. Anabolic steroids have been thought to increase blood pressure through a variety of possible mechanisms, but it is their sodium retaining properties which are the primary cause of high blood pressure in most users. When anabolic steroids are administered they inhibit an enzyme known as 11-beta hydroxylase, which leads to the increased production of deoxycorticosterone and the subsequent retention of sodium and water. While anabolic steroids can vary substantially in their ability to influence this enzyme, as a general rule, the higher the dose employed, the more this enzyme is inhibited. Therefore, high dose users are more likely to experience elevated blood pressure compared to low-dose users.

High blood pressure is frequently implicated as a risk factor in cardiovascular disease and rightly so, but what about its effect on renal (kidney) function? Unfortunately, high blood pressure is a direct cause of renal stress and a leading contributor in the development of kidney failure. In fact, high blood pressure is the #2 cause of kidney failure in the United States right behind diabetes, being responsible for a full 28+% of documented cases and this number has only continued to grow over the last decade. With high blood pressure being one of the most common side effects associated with anabolic steroids use, one might think that it would garner more attention among the drug using community, but sadly, it does not.

When blood pressure is high, blood vessels stretch so that blood can flow more easily. This chronic stretching eventually weakens and scars the blood vessels of the kidneys, damaging them and impairing their ability to work properly. Once damaged, they become inefficient at waste and fluid removal. On top of the resulting toxin build-up, the inability to remove excess fluid can elevate blood pressure even more, resulting in a dangerous cycle.

Although anabolic steroids use alone is a potentially significant contributor to kidney disease/failure, as mentioned above, there are usually multiple causes involved in its development. Another potential risk factor is the use of nephrotoxic agents, such as NSAID’s. With anti-inflammatory drugs like Ibuprofen being routinely implicated in the development of kidney disease/failure and with many bodybuilders regularly using these drugs to treat various aches and pains, this risk factor should not be ignored. For anabolic steroids using bodybuilders, the over-use of NSAID’s may be all it takes to enter stage 1 kidney failure, followed by entrance into the later stages if not addressed. Therefore, nephrotoxic drugs should be used sparingly and only as needed. In cases of chronic pain and inflammation, one should seek speak with their physician regarding alternative treatments.

If you have been around the bodybuilding nutrition scene for any length of time, you will be familiar with the warnings associated with a high protein diet. While numerous studies have demonstrated the relative safety of a high protein diet, excess protein intake will still place additional strain on the kidneys. While this is not an issue in otherwise healthy people, it is like throwing gasoline on a burning fire in those with already compromised kidney function.

This is good reason to rely on the protein-sparing effects of carbohydrates and fats in the off-season, rather than using excess protein to meet one’s caloric demands. There has yet to be any published research demonstrating the benefits of a very high protein diet for the purpose of muscle growth, but perhaps we should first define the term “very high protein” diet. Among bodybuilders, 1-2 grams of protein per pound of bodyweight is considered to be typical in terms of daily protein intake.

In my opinion, this amount is ideal for optimizing muscle growth, assuming that adequate carbohydrate and fat is consumed in order to meet energy requirements. I see no need to go beyond this amount and at times have even questioned the validity of 2 grams. Obviously, there are instances in which a bodybuilder will need to consume more than the standard 1-2 grams per pound, such as during pre-contest prep, when carbs & fats have been reduced in an effort to shed bodyfat, but during the off-season, when muscle growth is the objective, I have yet to see a bodybuilder experience measurably greater growth when venturing beyond this pre-determined amount.

The take home message here is that there is no clinical evidence to suggest that protein consumption beyond the standard range supplies additional muscle building benefits, but we do know that the kidneys are responsible for processing protein, with larger amounts increasing the work-load on the kidneys. In those with normal kidney function, excess protein consumption does not appear to contribute to a decline in kidney function, likely because the stress generated by a high protein diet alone is not great enough to produce such an effect. However, in combination with other risk factors, very high protein diets (above 1-2 grams/pound) are associated with a worsening of kidney function. Therefore, it does not make any sense to follow a potentially injurious diet in the absence of documented benefits.

Excess protein is not the only dietary consideration in the management of high blood pressure. Sodium also plays a role. Unlike anabolic steroids, which indirectly increase sodium retention as a consequence of use, we have no excuse for ignorance when it comes to the deliberate consumption of excess sodium. This is something that is easily within our control and while not all pre-made foods list sodium content on their packaging, as a bodybuilder you shouldn’t be eating many of these foods anyway. When attempting to manipulate sodium to our advantage, there are 2 primary factors we need to concern ourselves with. They are total intake and consistency of intake. Most bodybuilders will require slightly more sodium than a sedentary individual of equal bodyweight, due to the sodium loss that occurs during training via perspiration. Those bodybuilders who work in hot environments and/or have manual labor jobs will need to make further adjustments according to need.

The body is constantly regulating sodium levels in order to maintain/establish homeostasis (balance), as the proper balance of electrolytes is critical for the preservation of life. Aldosterone, a anabolic steroids hormone produced by the adrenal glands, plays a key role in maintaining this balance through the regulation of sodium levels within the body. When sodium levels are low aldosterone levels increase, causing the body to excrete less sodium. When sodium levels are high, aldosterone levels decrease, causing the body to excrete more sodium. The body is in a constant state of evaluation, with even the slightest changes in sodium levels initiating a change in aldosterone concentration.

By maintaining a fairly consistent sodium intake, the body is only required to make subtle adjustments in order to maintain homeostasis, but when it is exposed to large fluctuations in sodium due to an ever-changing diet, aldosterone concentrations are altered dramatically. This can cause substantial increases in water retention and as a consequence, significant elevations in blood pressure. Therefore, a bodybuilder would likely be better off consistently consuming slightly more sodium than needed, rather than eating low sodium on most days, but high sodium on others. In some cases it can take the body several days to restore proper water balance after a sodium splurge, during which times blood pressure can remain elevated.

Another risk factor associated with kidney disease/failure, and which is heavily connected to the first, is the unwillingness to go off anabolic steroids for a prolonged period of time. Fearing the loss of muscle tissue, many of today’s bodybuilders remain on anabolic steroids 365 days a year. Now, most of the side effects associated with anabolic steroids use are transient, and kidney stress is no exception (in most cases), but when these stressors remain in place indefinitely, the affected organ(s) never get a chance to rest. For those who have already entered into Stage 1 kidney failure or worse, this has potentially dire ramifications, as the body never has a chance to normalize itself and may be pushed into later stages of kidney failure. Needless to say, a little prudence in matters such as this can go a long way in making a positive impact on one’s health.

Finally, dehydration can have a negative effect on kidney function by reducing blood flow to the kidneys. As a result, the kidneys are unable to properly remove toxins from the bloodstream, resulting in toxin build-up; a condition known as azotaemia. The kidneys require adequate blood flow in order to perform their job properly and nothing reduces blood flow more quickly than dehydration (aside from extensive blood loss). In fact, if water is completely withheld, death can result in as little as 2-3 days.

Kidney damage is not uncommon among pre-contest bodybuilders who frequently utilize diuretics in an effort to present a dry appearance onstage. Due to the potent nature of these drugs, one can simulate a state of severe water deprivation within days and in some cases mere hours. With protracted and/or repeated use, and depending on the dose administered, kidney damage can and often does occur to varying degrees.

Regardless of the cause(s), high blood pressure leading to kidney damage is a very real concern among anabolic steroid-using bodybuilders. The relative scarcity of outwardly discernible symptoms has earned it the moniker “the silent killer”, as many of those afflicted with the condition are unaware of its existence. This makes it potentially more dangerous than many other side effects, which manifest themselves openly.

As mentioned above, excessive protein & sodium intake, the use of NSAID’s, inadequate water consumption, and a refusal to take periodic breaks from anabolic steroid use, all serve to further compound the problem. With most bodybuilders being exposed to one or more of these risk factors, it makes sense to take steps to minimize their deleterious effects on the body, especially in those who individuals who have already entered into the beginning stages of kidney failure.

Supplementation is also a viable option in the prevention of kidney disease/failure. One of the most common classes of kidney support supplements are those which help reduce blood pressure. Fortunately, there are several clinically validated OTC supplements which have proven effective in the alleviation of this malady. Hawethorn berry is one of the most heavily researched of the bunch and at optimal dosage is quite effective at reducing blood pressure. Co-Q10, as well as celery seed extract, have also been shown to provide considerable benefit in this area. Other classes of supplementation include detoxifiers, antioxidants, and alkalinizers, as well as single compounds, such as vitamin B-6 and L-Carnitine, although not all of these products may be beneficial in every case. Underlying causes, as well as disease progression, should be taken into consideration when designing a kidneys support program.

Without doubt, ignorance is the #1 cause of kidney dysfunction in drug-using bodybuilders today. Often, it doesn’t take more than a few simple adjustments to mitigate further damage and bring things under control. I encourage all bodybuilders to regularly evaluate their kidney health through physician monitored bloodwork, as the kidneys do not possess the same self-rejuvenating capabilities as the liver. Once damage is sustained, it is oftentimes permanent. Therefore, preventative action is a must.

Friday, June 20, 2014

How to cycle Clen and Clen Side Effects and Doses

Clenbuterol is a beta-2 agonist and is used in many countries as a broncodilator for the treatment of asthma. Because of it’s long half life, Clenbuterol is not FDA approved for medical use. It is a central nervous system stimulant and acts like adrenaline. It shares many of the same side effects as other CNS stimulants like ephedrine. Contrary to popular belief, Clenbuterol has a half life of 35 hours and not 48 hours.

Dosing and Cycling Clenbuterol comes in 20mcg tablets, although it is also available in syrup, pump and injectable form. Doses are very dependent on how well the user responds to the side effects, but somewhere in the range of 5-8 tablets per day for men and 1-4 tablets a day for women is most common. Clenbuterol loses its thermogenic effects after 6-8 weeks when body temperature drops back to normal. It’s anabolic/anti-catabolic properties fade away at around the 18 day mark. Taking the long half life into consideration, the most effective way of cycling Clen is 2 weeks on/ 2 weeks off for no more than 12 weeks. Ephedrine can be used in the off weeks. Ephedrine will raise metabolic levels by about 2-3 percent and 200mg of DNP raises metabolic levels by about 30 percent. Clenbuterol raises metabolic levels about 10 percent and it can raise body temperature several degrees.

DNP is by far the most effective fat burner but many people will never use it because of the risks associated with it. It also offers no anti-catabolic benefit. Although it does have anti-catabolic effect, ephedrine short half life prevents it from being all that effective.

As far as side effects, Clenbuterol’s are certainly milder than DNP’s, and some would even say milder than an ECA stack. There is no ECA-style crash on Clenbuterol and many users find it easier on the prostate and sex drive. This may in part be due to the fact that Clen is generally used for only 2 weeks at a time.

Side effects

  • Nausea
  • Nervousness 
  • Dizziness
  • Drowsiness 
  • Dry mouth
  • Facial flushing
  • Headache
  • Heartburn
  • Increased blood pressure
  • Increased sweating
  • Insomnia
  • Lightheadness
  • Muscle cramps
  • Tremors
  • Vomiting
  • Chest pain

The most significant side effects are muscle cramps, nervousness, headaches, and increased blood pressure. Muscle cramps can be avoided by drinking 1.5-2 gallons of water and consuming bananas and oranges or supplementing with GNC potassium tablets at 200-400mg a day taken before bed on an empty stomach. Headaches can easily be avoided with Tylenol Extra Strength taken at the first signs of a headache. You may need to take double the recommended dose.

Post-Cycle Therapy: Clenbuterol is used post cycle to aid in recovery. It allows the user to continue eating large amounts of food, without worrying about adding body fat. It also helps the user maintain more of his strength as well as his intensity in the gym. Diet: Roughly the same as on cycle.

Fat loss: The most popular use for Clenbuterol, it also increases muscle hardness, vascularity, strength and size on a caloric deficit. For the most significant fat loss, Clen can be stacked with T3. Diet: A high protein (1.5g per lb of bodyweight), moderate carb(0.5g to 1g per lb of bodyweight), low fat diet (0.25g per lb of bodyweight) seems to work best with Clenbuterol.

Clenbuterol has mild steroid-like properties and can be used by non anabolic steroids using bodybuilder to increase LBM as well as strength and muscle hardness. Diet: A moderate carb, high protein, moderate fat diet work well.

Stimulant/Performance Enhancement: It can be used as a stimulant, but an ECA stack may be a better choice because of it’s much shorter half-life. Diet: To take full advantage of the stimulatory effects of Clen, Carbs must be included in the diet. Keto diet do not work well in this case.

Is Clen for you?
The same precautions that apply to Ephedrine must be applied to Clenbuterol, although some people find ECA stacks harsher than Clenbuterol. It should not be stacked with other CNS stimulants such as Ephedrine and Yohimbine. These combinations are unnecessary and potentially dangerous. Caffeine can be used in moderation before a workout for an extra kick, although its diuretic effects may shift electrolyte balance. Drink more water if you use Caffeine.

Most users that report bad side effects and discontinue use are those who use high doses right at the start of the cycle. The worst side effects occur within the first 3-4 days of use.
A first time user should not exceed 40mcg the first day.

Example of a first cycle:
Day1: 20mcg
Day2: 40mcg
Day3: 60mcg
Day4: 80mcg
Day5: 80mcg(Note: Increase the dose only when the side effects are tolerable)
Day6-Day12: 100mcg
Day13: 80mcg (Tapering is not necessary, but it helps some users get back to normal gradually)
Day14: 60mcg
Day15: off
Day16: off
Day 17: ECA/ NYC stack

Example of a second cycle:
Day1: 60mcg
Day2: 80mcg
Day3: 80mcg
Day4: 100mcg
Day5: 100mcg
Day6-Day12: 120mcg
Day13: 100mcg
Day14: 80mcg
Day15: off
Day16: off
Day 17: ECA/ NYC stack

Do not take Clenbuterol Past 4pm and drink plenty of water: 1.5-2 gallons a day.
All brands are not equal when it comes to Clenbuterol, different brands will yield different results. That about covers everything.

Thursday, June 5, 2014

GP Oxan (Anavar) by Geneza Pharmaceuticals

GP Oxan by Geneza Pharmaceuticals is an oral steroid which contains 10mg of the hormone Oxandrolone. This steroid is commonly called Anavar, or "Var" for short.

Anavar is considered one of the mildest steroids that there is. It is mildly anabolic and mildly androgenic. Even though it is a C-17 oral, it still has minimal effect on liver values even at higher doses. Var also isn’t known by bodybuilders as the steroid for big mass gains. Rather, the mass that is gained by GP Oxan will be quality gains, and gains that likely to be kept after the steroid is no longer being used. Users of Anavar often note a very good increase in strength. Some bodybuilders compare the strength increases seen by its use to be similar to GP Oxy on a mg for mg basis, but without the extra side effects! Because of this, and the fact that users won’t gain a lot of weight because of the drug, Var is a very popular drug for powerlifters and sports related athletes.

Due to its extremely mild nature, Var is also one of the most popular steroids amongst women bodybuilders. Anavar has also been shown in studies to actually decrease bodyfat during use, making it a great choice for bodybuilders who are in the cutting phase of their training.

GP Oxan is also very mild when it comes to shutting down the body’s ability to produce testosterone, making it a great choice for those looking to "bridge" between cycles while allowing the body to recover. Those looking to stack Anavar with something may chose a low dose of a testosterone to do with it. Also, the classic Anavar / Primo cycle is one of the most popular cutting cycles ever. This cycle provides one with quality muscle gain and minimal side effects and risk.

Clearly, GP Oxan is a great all around steroid. Male bodybuilders will typically use Anavar in doses of 50-100mg a day for 6-12wks. Var has a relatively short half life of about 8 hours. So one may chose to split dosages throughout the day in order to keep blood levels as stable as possible. Women bodybuilders typically find a dosage of 2.5-10mgs to be effective for promoting muscle gains and strength without the great risk of side effects.