Showing posts with label Testosterone. Show all posts
Showing posts with label Testosterone. Show all posts

Friday, April 17, 2015

Omnadren 250


Omnadren is a combination of 4 separate test esters. Older versions of the drug list the final two esters as isohexanoate and hexanoate. However, it should be noted that hexanoate is simply another word for caproate so the drugs esters have not actually been modified. Most commonly, people will correlate Omnadren 250 with its cousin Sustanon 250, since they are both a blend of 4 test esters. The only difference between the two lies in the last and most concentrated- ester. Whilst Omnadren contains the caproate ester, Sustanon contains the decanoate ester in the same concentration.

It is also not uncommon to hear people refer to Omnadren as a superior version of testosterone since it boasts 4 esters instead of 1 (or none). This should be taken with a grain of salt. All testosterones produce very similar effects while the ester simply delays the release of the compound into the body which has two immediate consequences. The first, being less important, is injection frequency. This has become a hotly debated issue recently& on the one side are those who advocate injections only once or twice per week. Frequently their arguments are supported with cycle results which have yielded good gains. On the other side and perhaps the more scientific side- are those who advocate injections at least every other day (EOD) or ever day (ED). One has only to glance at the ester constitution in Omnadren 250 to understand why this may be. Such small concentrations of the shorter esters (propionate and phenylpropionate) are rendered practically useless when Omnadren is injected once or twice per week. Furthermore, when injecting only a few times per week the peaks and valleys of concentration in the blood are not desirable. We want our blood concentration of the drugs to be as high as they can be relative to dose- as long as they can be. Obviously, this is not the case when fast acting esters are introduced and subsequently dissipated before another injection is given.

As the longest ester in Omnadren (caproate) is slightly faster acting than the longest ester in Sustanon (decanoate), users will notice an increase in their testosterone levels sooner with Omnadren than with Sustanon. This has a few consequences which we shall examine now. First of all, since testosterone aromatizes (converts) to estrogen, a buildup of this female hormone will occur more rapidly. With estrogen increase follows the inevitability of increased water retention. This is significant for 3 reasons: First, the users strength will increase. Secondly, the users size will increase, and finally, definition in the muscles will begin to dissipate. As an obvious result, Omnadren 250 is typically used more for bulking than cutting. The extent of these effects are highly dictated by the users diet and training habits, although it is also easily controlled with the proper use of anti-estrogen drugs such as Nolvadex, Armidex, Proviron, and a myriad of others.

Testosterone is a highly anabolic and androgenic hormone, it has an anabolic (muscle building) rating of 100, making it a good drug to use if one is in pursuit of more size and strength. And if you arent in pursuit of more size and strength, then why would you be reading this, right? Well, lets get on with it and look at exactly what makes testosterone a good mass builder. Firstly, testosterone promotes nitrogen retention in the muscle the more nitrogen the muscles holds the more protein the muscle stores. Testosterone can also increase the levels of the highly anabolic hormone, IGF-1, in muscle tissue. Even the aromatized part of testosterone that turns into estrogen may increase levels of IGF, and sensitivity to it. Testosterones actions come mostly from its binding to the androgen receptor to promote A.R dependant mechanisms for both muscle gain and fat loss. Thankfully, it also significantly increases the concentrations of the A. R in cells critical for muscle repair and growth and A.R in muscle. Testosterone induces changes in shape, size and also can change the appearance and the number of muscle fibers. Androgens like the testosterone(s) found in Omnadren can protect your hard earned muscle from the catabolic hormones, whether those hormones occur from exercise or other stress.

Omnadren Side Effects

There are strong androgenic side effects, which are pronounced with Omnadren (as with all testosterones). Oily skin, acne, increased body/facial hair, and depending on the individual an increase in aggressiveness can occur. Omnadren 250 can also be hard on the hairline. This is partly due to the conversion of the testosterone into dihydrotestosterone (DHT). Test is converted to DHT via the 5-alpha reductase enzyme. While DHT is more potent than test at the androgen receptor (the double bond is removed from the carbon4-carbon5 bond and replaced with a hydrogen atom on each) and is responsible for some growth. It can also cause some negative side effects as well. Testosterone, because of this bond is actually much more anabolic, in practical terms, because it For example: DHT formation in the scalp is suspected of causing/expediting male pattern baldness. To possibly combat this, one can use finasteride. This drug will inhibit the conversion of testosterone to DHT but many users will report that since DHT is more potent at the androgen receptor than test, gains in muscle mass as well as strength will diminish. On the other hand, a lack of DHT caused by blocking 5-AR can sometimes cause gynocomastia.

Omnadren Cycles

Typically cycles which contain Omnadren 250 will be around 12-16weeks. The idea is that it will take at least 2 weeks for the compound to become fully active in the body, and most users will report an additional 1-3 weeks until the effects of Omnadren are truly felt. As a result, gains from Omnadren are not typically noticed for about 1 month after the first injection. What most people mean by this is that although the actual drug is already active, gains arent realized immediately. The majority of users will supplement a fast acting oral drug such as Dianabol or Anadrol in the first 4 weeks of a cycle which is thought of as a kickstart until the effects of the Omnadren are fully felt. As mentioned above a typical weekly dose of Omnadren can range from 500mg-1000mg per week. Those who are new to steroids and cycling should generally start with a minimal dose so as to better judge how their own bodies will react to the synthetic testosterone. Id suggest beginners stick with 2 amps per week, if theyre inclined to use this preparation.

Friday, October 31, 2014

Sustanon 250

Sustanon 250 is the trade name for a mixture (or ‘blend’) of 4 different variations of esterified Testosterone in a particular ratio. It typically contains: 30mg of Testosterone Propionate, 60mg of Testosterone Phenylpropionate, 60mg of Testosterone Isocaproate, and 100mg of Testosterone Decanoate for a total of 250mg worth of combined Testosterone esters (hence the number 250 in the name Sustanon 250). The idea in combining all of these different Testosterone esters is to provide a Testosterone drug that will provide the user with both a fast immediate release of Testosterone followed by a slower more extended release. The opposite of such a drug would be single forms of esterified Testosterone, such as a Testosterone Propionate product, which, of course, contains nothing but Testosterone Propionate in the vial.

Sustanon was developed and manufactured by Organon and it was in the early 1970s that it entered the market. The idea behind it was to provide a preparation of Testosterone that would have an advantage over single esterified Testosterone products in a medical and clinical setting. The idea here was also that of convenience, as Sustanon 250 requires more infrequent injections than does Testosterone Propionate or Testosterone Suspension, for example. What is interesting to note is that Sustanon 250 was never approved for use or sale in the United States, but Sustanon 250 remains a very popular drug on the international market. Sustanon 250 is most likely one of the most popular Testosterone preparations in use by bodybuilders and athletes. It was commonly thought that this was the case due to misconception that its more potent than single esterified forms of Testosterone, but this is not true. Esters attached to different anabolic steroids only affect the half-life and release time of whatever anabolic steroid they are bound to. In the case of Sustanon 250, there are four different esterified types of Testosterone to be considered – but Sustanon 250 is no more ‘potent’ of a Testosterone product than a straight Testosterone Enanthate preparation, for example.

The real true and primary reason for its popularity among athletes and bodybuilders is instead the amount of steroid one is getting for the money spent. A blend of four different esterified Testosterone variants is considered a great value for the money spent in comparison to the purchase of a single esterified Testosterone variant. However, over the years this price difference has not proven to be extremely advantageous over other forms of Testosterone. The sheer truth of the matter is that Sust 250 was not developed for athletes and bodybuilders, but instead with medical application in mind, and it is therefore an optimized product for those requiring medical treatment from it. The idea with this product was to provide patients with a far more convenient and comfortable dosing schedule where administration of the drug is concerned. Many patients prescribed it need only to worry about an injection every 3 – 4 weeks. As a bodybuilder or athlete, this is very unrealistic seeing as though athletes and bodybuilders would require injections of this product weekly, and blood plasma levels of Testosterone as a result would end up peaking to the same levels in the same amount of time that any other type of Testosterone product would end up doing. Therefore, the perceived benefits of Sustanon really do not apply to bodybuilders or athletes, or to individuals looking to use it for the purpose of performance/physique enhancement.

The properties of Sust 250 is what one would expect from any Testosterone preparation. It is important to remember that Sustanon 250 is simply only Testosterone with a mixture of different release times. Therefore, the typical properties and effects are exactly what any expectations would be from Testosterone.

Testosterone is literally the original anabolic steroid, produced naturally within all humans and most animal species. It is considered the safest anabolic steroid one could use, due to the fact that it is the hormone that each individual’s body already produces, already uses, and is already accustomed to. Therefore, the use of Testosterone for the purpose of performance and physique enhancement is simply the equivalent of introducing more of a hormone into the human body that it already manufactures and uses.

Friday, August 8, 2014

Alcohol's Effects on Testosterone


The majority of research conducted in the past 25 years, in both animals and humans, has found that alcohol inhibits testosterone secretion. However, a new study found that alcohol can induce a rapid increase in plasma and brain concentrations of testosterone in some rodents. "We have demonstrated that there are very different results in the way two different groups of male rats form testosterone after acute administration of alcohol," said Robert H. Purdy, senior staff scientist in the department of neuropharmacology at The Scripps Research Institute and senior author of the study. "These differences in animals may reflect similar individual differences in humans, and provide new insights for understanding individual differences in the behavioral and endocrine pathology associated with alcohol abuse."

According to the ACER report: Researchers "injected either alcohol or 1,1-dideuteroethanol (2 g alcohol/kg body weight) into the abdominal cavities of two groups of rats, 30 un-operated and 24 adrenalectomized and castrated (ADX/GDX) Wistar males. 1,1-dideuteroethanol is a nonradioactive form of alcohol in which two of the hydrogen atoms on carbon atom #1 of ethanol have been replaced by deuterium atoms, which can then be traced."

They then used mass spectrometry to determine both the amount of neuroactive steroids present and the degree of deuterium in specific neuroactive steroids isolated from brain samples.

The resarchers found that concentrations of testosterone increased fourfold in the frontal cortex and threefold in the plasma of the un-operated rats 30 minutes after alcohol administration. ADX/GDX rats had testosterone concentrations that were only five percent of those found in the un-operated rats after alcohol injection. The findings demonstrated that alcohol oxidation is directly linked to testosterone biosynthesis, the authors said.

"Our finding of a direct link between alcohol administration and the level of the neuroactive steroid testosterone in the brain of these experimental animals was unanticipated from prior studies with another species of rats," Purdy said.

"Although many other studies clearly demonstrate that chronic consumption of high dosages of alcohol appears to be consistently inhibitory and suppresses reproductive function," said Dennis D. Rasmussen, research associate professor in the department of psychiatry at the University of Washington, "this study raises the possibility that episodes of alcohol consumption may also at least temporarily increase testosterone levels, with the direction of the response likely being dependent upon a variety of factors, including dosage and personal characteristics.

"This particular dosage produced blood alcohol levels and behavioral responses consistent with intoxication. So, alcohol consumption, under at least some conditions and by at least some individuals, may acutely stimulate testosterone levels in the plasma and brain of both males and females and thus could elicit some of the behavioral effects associated with increased testosterone levels, such as increased libido or aggression."

Rasmussen said, his findings join those of two other studies in which alcohol administration increased plasma testosterone levels in a gender- and dose-dependent manner. "Together these studies are important," he said, "because they illustrate that what has become a largely accepted principal - that alcohol consumption inhibits plasma testosterone levels and reproductive function - is not universally true."

Rasmussen suggested that future research build upon and add to previous findings regarding alcohol's effects on testosterone. "It would be important to determine whether lower dosages of alcohol, which do not induce rapid pronounced intoxication and ataxia, would also produce the acute increase in testosterone, and whether this response to lower dosages would be consistent across different strains of rats. Also, does tolerance develop with repeated administrations?

"Does this increase in testosterone occur following elective self-administration of alcohol? Finally, and probably most interesting, what role might the demonstrated changes in testosterone play in behavioral responses to acute ethanol consumption? Are there gender differences in these responses? And, if the responses do occur in females, are they different during different stages of a woman's cycle?"

Friday, May 16, 2014

Testosterone for Women


A women in her late twenties, came to see me complaining about her difficulty in losing weight. After taking a medical history, it was very difficult to tell what the basis of her problem was. She was working out daily, with a balance of aerobic exercise and weight training under the guidance of a qualified personal trainer. Her diet was a basic low carbohydrate/ high protein diet. Even more perplexing, she had been taking a caffeine/ephedrine thermogenic stack and had previously experimented with some diet drugs as well. Something was obviously wrong. I did blood tests to check all of her hormone levels. When the results came back, all of her hormones were in the normal range except for, you guessed it, testosterone! She had very low free testosterone level. It was equal to that seen in a postmenopausal women. This was an obvious source of her fat loss problem .

While the role of testosterone in maintaining muscle mass and losing body fat may be obvious to bodybuilders and athletes, it is a basic hormonal fact that is often absent in the medical community. It is known that many women begin to gain fat rapidly about ten to fifteen years before the menopause and also after. The connection between low to absent testosterone production and the deterioration of a healthy body composition is rarely made. Most women are often only given estrogens and progestins as hormone replacement therapy, but not testosterone. I have found in my medical practice that giving women estrogen and progesterone and not testosterone makes it almost impossible for them to lose weight/fat. With the scourge of increasing obesity in the USA, one would expect the medical community to pay closer attention to these issues. Yet the connection between sex hormones, and body composition is highly controversial.

Why is there such a controversy? Why is a hormone commonly used by farmers to fatten up livestock given to postmenopausal women at risk for obesity? Many doctors point to a recent study showing that when postmenopausal women given estrogen actually gained less weight than those not given estrogen. In this study 875 women were either put on .625 mg of oral estrogen a day or a placebo for three years. So does this mean that estrogen is actually a good fat-loss agent? Hardly! In this study, in spite of the publicity it was given, the authors note that when you control for lifestyle factors such as physical activity the effects of estrogen replacement therapy were insignificant.

From my clinical experience I have found that on the average when a young woman goes on birth control pills a 3-5 pound gain in fat mass can be expected, and at menopause with oral estrogens 4-8 pounds of fat mass gain can be anticipated - especially when oral estrogens are used. A recent controlled study showed that oral estrogens caused a gain in fat mass and loss in muscle, with a decrease in IGF-1 levels. This study is more consistent with my clinical observations.

So why isn’t testosterone more commonly given for weight loss in women? The medical community actually commonly believes testosterone causes obesity. This is due to a number of studies linking upper body obesity /abdominal obesity in women to elevated testosterone levels. Once again, this is a case of blaming one hormone as a "villain". In these women, they do in fact have higher than normal testosterone levels but their whole hormonal system is out of balance. Not only do they have high testosterone levels, but they also have poor insulin sensitivity as well as high insulin levels. Often these women have a metabolic problem of insulin resistance—which is associated with obesity. There is no serious evidence that testosterone replacement therapy for women will result in greater body fat – in fact the opposite is true.

With the social stigma against testosterone and anabolic steroids in general, and it is difficult enough to get a study approved on testosterone in men. Imagine how difficult it is to get a human use committee to approve a study on testosterone in women! However, there is one study that helped to illuminate the potential for androgens to help women lose fat. Lovejoy et al, in 1996, compared the effects of nandrolone decanoate and the anti-androgen drug spironolactone on body composition in obese, postmenopausal women. The dose given the nandrolone group was low – 30 mg every other week. All women in the study were put on a calorie restricted diet (500 calories below lean mass maintenance), and were told not to change their exercise habits. After nine months, the women receiving nandrolone lost an average of 3.6 percent of their bodyfat while the placebo group lost only 1.8 percent and the spirolactone (an anti-androgen) only .5 percent. Nandrolone doubled the rate of fat loss over the placebo and the anti-androgen group barely lost any fat at all – the role of androgens in fat loss is clearly demonstrated. Even more impressive, the nandrolone group actually gained an average of roughly four pounds of lean mass in spite of the calorie restriction while the placebo and anti-androgen groups lost over two pounds of lean mass. Nandrolone also did not produce insulin resistance as androgens have been previously believed to do.

Lovejoy’s group were impressed by the ability of nandrolone to produce increased muscle mass in spite of overall weight loss. Keep in mind that dose was fairly small and only given every other week, and that these women were put only somewhat extreme calorie restricted diets without being put on a weight training program. Imagine the improvement in body composition had these women been put on a balanced exercise program and were given a high protein diet in addition to their nandrolone!

Despite the positive result, the authors cautioned against using nandrolone decanoate as a weight loss therapy. There was a mild abnormality of blood lipids and a slight increase in abdominal fat in the nandrolone group. While these side effects were minor, I believe that if testosterone was used in this study instead of nandrolone, these effects would be smaller or non-existent. I also think that daily use of a testosterone gel would be more effective than a bi-monthly shot, since the gel would keep testosterone at a more physiological and consistent level whereas injections lead to huge up and down fluctuations.

It is clear to me, both from my clinical practice and from research, that testosterone is vital for women to preserve their lean mass and to prevent obesity. Not only will testosterone help mobilize body fat and negate some of the fat storing effects of estrogen, it is also extremely effective in building lean mass in women - even at small doses. Hormone replacement therapy that only includes estrogen and progesterone but leaves out testosterone is a curse of many a women’s fat loss program. This is not only a concern for postmenopausal women. Young women should think twice about using birth control pills. Birth control pills elevate estrogen and progesterone levels while drastically lowering testosterone levels. This is reason why many women experience large gains in fat as well as a decreased libido when using birth control pills.

Thursday, April 3, 2014

How Anabolic Steroids Work in your body


Most people who are close-minded only think of the negative effects of anabolic steroids. Many despise body builders or athletes who take anabolic steroids just to get faster results or becoming bigger and stronger. What’s interesting is that our body naturally produces anabolic steroids through the male hormone, testosterone. And if you actually have natural steroids in you, then why should people condemn those who are taking them for their own purposes?

The fact is anabolic steroids are actually very helpful especially to patients in hospitals who have lost amounts of body tissues due to chronic wasting. These supplements can help build not only muscles for bodybuilders or endurance for athletes, but they can also help build tissues for medical patients who need to have faster recovery for the tissues lost.

Steroids are lipids from cholesterol in the body, which is secreted by various glands. The anabolic steroids that are typically used in bodybuilding are actually synthetic derivatives of the male hormone, testosterone, which promotes the growth of bones and muscles.

Since anabolic steroids come from testosterone, it has the same effects as this male hormone. Like the testosterone, which is produced in a man’s testicles, steroids have also anabolic and androgenic effects. The former is the primary target of both athletes and bodybuilders.

Anabolic steroids have been a huge part in bodybuilding and used mostly for their advantages such as anabolic benefits including the increase of muscle strength and size, increase of energy levels during activities, for faster recovery time and to increase the oxidation rise of fat. What anabolic steroids do is that they increase the testosterone levels in the body without passing through the usual pathway for the synthesis of the hormone by directly adding testosterone into the bloodstream. Generally, anabolic steroids are used for increase in muscle mass. However, the anabolic and androgenic benefits of these supplements actually still depend on the steroid type used. Increasing the male hormone in one’s body does not exactly cause chemical reactions. However, this just basically amplifies the reactions that already exist between your body and the male hormone.

Anabolic steroids are basically “man-made” testosterone chemically altered to optimize the anabolic effects with the minimum androgenic consequences as possible. We ourselves produce steroids inside our body so what you will only be doing if you take in some more steroids is to increase its effects. However, even the best anabolic steroids have certain side effects especially when taken in at huge doses. In the end, it always goes down to discipline and how you take anabolic steroids moderately. If you abuse anabolic steroids, you might get the side effects that all people are afraid of. But if you follow directions and control your urge to want some more steroids for more benefits, then steroids may not be so bad for you. As long as discipline is integrated in your anabolic steroids intake, then not only can you finally get the body as well as the energy that you desire, you can also have a positive change in your mood and sleep patterns, prevent depression and symptoms of arthritis as well as have your bones strengthened.

Because of these benefits, steroids have become a very significant part in athletics as well as in bodybuilding. In fact, it almost seemed like bodybuilding is synonymous to anabolic steroids. But other than these two pursuits, anabolic steroids can also be used with other strenuous hobbies such as dancing, wall climbing, etc., so that you can have a better endurance and an increased level of energy during these activities. Because of this, people are able to train more, and thus improve more on what they are best at.

Friday, March 21, 2014

Nolvadex vs. Clomid


It seems like everyday questions concerning Post Cycle Therapy pop up, and weather one should use either Clomid or Nolvadex or a combo of both. I hope that this article may help to clear up some misconceptions.

While practically similar compounds in structure, few people ever really consider Clomid and Nolvadex to be similar. Its not just a common myth in steroid circles, but even in the medical community. This misconception originates from their completely different uses. Nolvadex is most commonly used for the treatment of breast cancer in women, while Clomid is generally considered a fertility aid. In bodybuilding circles, from day one, Clomid has generally been used as post-cycle therapy and Nolvadex as an anti-estrogen.

But as I intend to demonstrate this is in essence the same. I believe the myth to have originated because Nolvadex is clearly a more powerful anti-estrogen, and the people selling Clomid needed another angle to sell the stuff, so it was mostly used as a post-cycle aid. But few users really understand how Clomid (and also Nolvadex, logically) works to bring back natural testosterone in the body after the conclusion of a cycle of androgenic anabolic steroids. After a cycle is over, the level of androgens in the body drop drastically. The body compensates with an overproduction of estrogen to keep steroid levels up. Estrogen as well inhibits the production of natural testosterone, and in the period between the return of natural testosterone and the end of a cycle, a lot of mass is lost. So its in everybody’s best interest to bring back natural test as soon as humanly possible. Clomid and Nolvadex will reduce the post-cycle estrogen, so that a steroid deficiency is constated and the hypothalamus is stimulated to regenerate natural testosterone production in the body. That’s basically how the mechanism works, nothing more, nothing less.

Both compounds are structurally alike, classified as triphenylethylenes. Nolvadex is clearly the stronger component of the two as it can achieve better results in decreasing overall estrogen with 20-40 mg a day, than Clomid can in doses of 100-150 mg a day. A noteworthy difference. Triphenylethylenes are very mild estrogens that do not exert a lot, if any activity at the estrogen receptor, but are still highly attracted to it. As such they will occupy the receptor and keep it from binding estrogens. This means they do not actively work to reduce estrogen in the body like Proviron, Viratase or arimidex would (by competing for the aromatase enzyme), but that it blocks the receptor so that any estrogen in the body is basically inert, because it has no receptor to bind to.

This has advantages and disadvantages. The disadvantage is that when use is discontinued, the estrogen level is still the same and new problems will develop much sooner. The advantage is that it works much faster and has results sooner than with an aromatase blocker like Proviron or Arimidex. Therefor, when problems such as gynocomastia occur during a cycle of steroids one will usually start 20 mg/day of nolva or 100 mg/day of Clomid straight away, in conjunction with some Proviron or arimidex. The proviron or arimidex will actively reduce estrogen while the Clomid or Nolvadex will solve your ongoing problem straight away. This way, when use is discontinued there is no immediate rebound.

So which one should you use? Well personally, I’d have to say Nolvadex. Both as an on-cycle anti-estrogen and a post-cycle therapy. As an anti-estrogen its simply much stronger, demonstrated by the fact that better results are obtained with 20-40 mg than with 100-150 mg of Clomid. For post-cycle, this plays a key role as well. It deactivates rebound estrogen much faster and more effective. But most importantly, Nolvadex has a direct influence on bringing back natural testosterone, where as Clomid may actually have a slight negative influence. The reason being that Tamoxifen (as in Nolvadex) seems to be the best choice for Post Cycle Therapy.

Friday, February 28, 2014

Effects of Testosterone


Testosterone is a steroid hormone and it belongs from the group of androgen. It is the hormone found in birds, mammals and vertebrates. In mammals, ovaries of females and testicles of males secrete testosterone. Testosterone is the sex hormone in male and a basic anabolic steroid as well. Testosterone has its significance in the male reproductive tissues in which testis and prostate are included and it deals with the growth of the hair of the body. It is an essential component for health and well-being of a person.

Normally concentration of testosterone is greater in adult males as compared to females and it is nearly believed to be 7-8 times greater. Normally, the female body is more receptive and sensitive to hormones. It is the hormone, which is present in most vertebrates including the fish. That is the reason why Testosterone is an essential part of the body of human as well as other mammals and vertebrates.

Testosterone provides both the virilizing as well as the anabolic effects and some effects are considered both, as it is very difficult to make a distinction between them. When you talk about the anabolic effects, you see the strengthening of body and muscle mass and linear growth stimulation as well as the bone maturation. The virilizing or androgenic effects deals with the enhancement as well as the maturation of the organs related to sex in which the fetus scrotum and penis is of utmost importance. It also deals with the deepening of the voice, growth of different kinds of hair of the body. Other than these male secondary sex characteristics, they also deal with the postnatal effects in the case of both males as well as females and in that case, they are dependent on the duration of the circulation of the testosterone.

Normally the effects of testosterone are more in male adults as compared to the female adults but they are equally important for both the sexes at the same time. However, it is a fact that testosterone level may decrease in the adult life in the later part.

Among other uses of testosterone, it is the highly important and necessary ingredient for the sperm development in males. This hormone helps in activating the genes in the cells for the differentiation of Spermatogonia. Testosterone provides the physical energy and it maintains the trophism for the muscles. If high androgen levels are found in females, then it makes the menstrual cycle irregular and abnormal and that can happen in the healthy women as well.

Testosterone plays an important role in the maintenance of cardiovascular health. If testosterone level in controlled in the elderly men, then it can decrease the total cholesterol level and decrease fat body mass. It is not known to cause any kind of deleterious effects on the cancer of prostrate. It can play a role in the fight responding time as well. Normally the men who have high level of testosterone are likely to have the high blood pressure and in that way their chances of getting heart attack decreases. However, they are more receptive towards injuries, infections transmitted sexually and other bad habits like smoking.

Along with many other uses, testosterone has its significance in medical use as well. Main use of testosterone is for the treatment of males who have the problem of endogenous testosterone production. This type of disease is known as hypogonadism. In this case, normally the treatment is done through the testosterone therapy in which the replacement is done and then the testosterone levels are maintained in the normal range. However, the replacement therapy may work well for some people, and in other cases, it may cause some problems. It can help in reducing the infertility, it can correct the erectile dysfunction and it can reverse the effects of anemia as well.

Testosterone is effective in giving treatment for the low libido level during the women post-menopausal. Sometimes, the strategies of testosterone are done to prevent loss of bone mass and to deal with any kind of depression. However, some women may face the side effects like increase in their weight and in that case their body fat is not increased but they may face some changes in muscle density. Another risk is that if a woman goes through testosterone therapy then they might face risk of getting breast or any other kind of gynecological cancers up to some extent.

There are many benefits and some adverse effects of testosterone therapy. It can really help in managing the diabetes of type 2. Sometimes, low testosterone level may increase the risk of diseases of high intensity, so therapy is necessary and advised in that case. However, it must important to note that some health risks are also involved with the testosterone therapy and prostate cancer may come apparent after few months of the testosterone therapy treatment.

Testosterone can also be very useful for athletes as well in order to improve their performance drastically. However, it is commonly considered as the doping case in many sports of players use the testosterone. Many other anabolic steroids including the testosterone can be used to strengthen the muscle development. If testosterone is used properly then it makes the fastening repair of the of the muscles fiber.

There are many methods that have been deployed for the detection of testosterone in the athletes and the most common one is the urine test. Among many administration routes for the testosterone the ones that are being used mostly commonly are injectables, buccals, transdermal creams, and some kinds of gels along with few others as well. It is believed that some other methods and nasal sprays will come soon for this purpose.